One-pot Synthesis of Polyethylene glycol-based Polymeric Monolithic Stationary Phases for Capillary Ion Chromatography

  • Kenichi Tsuge Department of Chemistry and Biomolecular Science, Faculty of Engineering, Gifu University, Japan
  • David Marikah Division of Materials Engineering, Graduate School of Engineering, Gifu University, Japan
  • Puji Lestari Division of Materials Engineering, Graduate School of Engineering, Gifu University, Japan
  • Shunya Adachi Department of Chemistry and Biomolecular Science, Faculty of Engineering, Gifu University, Japan
  • Yasuhiro Okajima Department of Chemistry and Biomolecular Science, Faculty of Engineering, Gifu University, Japan
  • Lee Wah Lim Department of Chemistry and Biomolecular Science, Faculty of Engineering, Gifu University, Japan https://orcid.org/0000-0002-6897-531X
  • Toyohide Takeuchi Department of Chemistry and Biomolecular Science, Faculty of Engineering, Gifu University, Japan
Keywords: Capillary ion chromatography, Inorganic anion, Polymer-based monolithic capillary column, Poly(ethylene glycol) methyl ether methacrylate-bonded stationary phase

Abstract

Polyethylene glycol-based polymeric monolithic stationary phases (capillary columns of 0.32 mm I.D.) were successfully prepared via one-pot-single-step reaction and were use in ion chromatography for the separation of several common inorganic anions. It should be noted that the prepared polyethylene glycol-monoliths were able to retain and separate the anions even though there were no ion-exchange sites. The retention mechanism was found to be based on the eluent cations trapped among the polyethylene glycol chains and worked as the anion-exchange sites. Several parameters such as the reaction conditions, monomer:porogen ratios, type of eluents, etc., were investigated. The relative standard deviations obtained for the retention times and signal intensities were less than 5 and 10% respectively. Theoretical plate numbers obtained for the separation of these anions were calculated to be in the range of 700-4300 plates for capillary columns of 10 cm in length.

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Polyethylene glycol methyl ether methacrylate (PEGMEMA) was reacted with ethylene dimethacrylate (EDMA) together with an initiator (AIBN) and biporogenic solvent (1-propanol and 1,4-butanediol) via one-pot-single-step reaction. The PEG chains present on the synthezied monoliths were able to trap eluent cations (M+) and have ionic intereactions with the analyte anions (A-) as well as the eluent anion (E-).
Published
2020-12-30
How to Cite
Tsuge, K., Marikah, D., Lestari, P., Adachi, S., Okajima, Y., Lim, L. W., & Takeuchi, T. (2020). One-pot Synthesis of Polyethylene glycol-based Polymeric Monolithic Stationary Phases for Capillary Ion Chromatography. Journal of the Indonesian Chemical Society, 3(3), 158. https://doi.org/10.34311/jics.2020.03.3.158